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In Alzheimer’s disease, glutamate excitotoxicity which can damage neurons through chronic activation is exacerbated by deficiency of ABCA7, the second strongest genetic risk factor for the disease. The findings highlight ABCA7 and glutamate–GABA signaling as potential therapeutic targets.
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US stock market rebounds as oil prices stop spiking
Фото: Kevin Lamarque / Reuters
Collection. The collector walks the shadow stack, marks all reachable objects, then sweeps unmarked objects and frees their memory. The allocation threshold grows after each cycle to avoid excessive collection.